drugset / Trial / NCT02251171
Effects of Steady-state TPV/RTV on the Single-dose Pharmacokinetics of Rifabutin and the Effects of Single-dose Rifabutin on the Steady-state Pharmacokinetics of TPV in Healthy Adult Volunteers
NaSingle-groupOpen-labelTreatment
Summary
Study to determine the effects of steady-state Tipranavir (TPV) / Ritonavir (RTV) (500mg/200mg bid) on the single-dose pharmacokinetics of Rifabutin (RFB) and to determine the effects of single-dose RFB on the steady-state pharmacokinetics of TPV 500mg (co-administered with RTV 200mg)
Timeline
- Start
- 2003-08
- Primary completion
- 2003-10
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rifabutin | Small molecule | 150 mg | — |
| Subject | Tipranavir | Small molecule | 500 mg | — |
| Background | Ritonavir | Other / unclassified | 200 mg | — |
Indications
No indication recorded.