drugset / Trial / NCT02251873
Evaluation of the Pharmacokinetic Interaction of Steady State Tipranavir and Ritonavir or Tipranavir and Ritonavir With Single Dose Didanosine in Healthy Volunteers
RandomizedParallel-groupOpen-labelTreatment
Summary
Study to characterise the effects of concurrent tipranavir (TPV) and ritonavir (RTV) administration on the single dose pharmacokinetics of didanosine (ddI), to characterise the effects of single-dose ddI on the pharmacokinetics of TPV and RTV and to assess the short-term safety of this combination
Timeline
- Start
- 2001-09
- Primary completion
- 2002-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Didanosine | Small molecule | 400 mg | — |
| Subject | Ritonavir | Other / unclassified | 100 mg | — |
| Subject | Ritonavir | Other / unclassified | 200 mg | — |
| Subject | Tipranavir | Small molecule | 500 mg | — |
| Subject | Tipranavir | Small molecule | 750 mg | — |
Indications
No indication recorded.