drugset / Trial / NCT02253277

Safety and Tolerability of Combined Treatment With Nilotinib and Ruxolitinib in CML and Ph+ ALL Patients

NCT02253277

Phase 1 Completed 5 enrolled Novartis Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

In this study it was the rationale to evaluate the safety and tolerability of the combined administration of nilotinib and increasing dose of ruxolitinib in patients with chronic myeloid leukemia and patients with Philadelphia positive acute lymphoblastic leukemia.

Timeline

Start
2015-02-18
Primary completion
2018-03-06
Completion
2018-04-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Nilotinib Small molecule 300 mg
Subject Ruxolitinib Small molecule