drugset / Trial / NCT02256722
In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects
RandomizedCrossoverOpen-labelTreatment
Summary
Study to compare the metabolic and electrolyte effects of a single oral dose of 320 mg ritobegron administered alone or with a pre- and comedication with bisoprolol, propranolol and acipimox. In addition, to compare the metabolic and electrolyte effects of a single dose of 320 mg ritobegron with those of a single inhalatory dose of 100 μg salmeterol
Timeline
- Start
- 2005-10
- Primary completion
- 2005-11
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acipimox | Small molecule | 500 mg | — |
| Subject | Bisoprolol | Other / unclassified | 10 mg | — |
| Subject | Propranolol | Small molecule | 160 mg | — |
| Subject | Ritobegron | Small molecule | 320 mg | Oral |
| Comparator | Salmeterol | Other / unclassified | 100 ug | Inhaled |
Indications
No indication recorded.