drugset / Trial / NCT02257476

Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors

NCT02257476

Phase 1 Completed 22 enrolled Emory University Amgen · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find the safest dose level of an approved drug, carfilzomib, in solid tumors when given over a different period of time than normally used. The study will also use markers in blood from routine blood draws to help check the levels of the drug. Lastly, the study will check how well this drug works with regards to keeping cancer cells from growing with the new time frame of delivery.

Timeline

Start
2014-08
Primary completion
2016-11
Completion
2016-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified 20 mg/m2 Intravenous
Background Dexamethasone Small molecule 8 mg Oral

Indications