Neuromuscular Blockade for Post-Cardiac Arrest Care

Phase 2 Completed 83 enrolled Beth Israel Deaconess Medical Center Beaumont Hospital · collab Brigham and Women's Hospital · collab University of Alabama at Birmingham · collab University of Pittsburgh Medical Center · collab

RandomizedParallel-groupSingle-blindOther

Summary

The main purpose of this study is to evaluate if neuromuscular blockade improves lactate clearance (and preliminary secondary clinical outcome measures) as compared to usual care in post-cardiac arrest patients undergoing targeted temperature management.

Timeline

Start: 2014-10
Primary completion: 2019-05-29
Completion: 2019-05-29

Publications

Moskowitz A, Andersen LW, Rittenberger JC, Swor R, Seethala RR, Kurz MC, Berg KM, Chase M, Cocchi MN, Grossestreuer AV, Liu X, Holmberg MJ, Callaway CW, Donnino MW. Continuous Neuromuscular Blockade Following Successful Resuscitation From Cardiac Arrest: A Randomized Trial. J Am Heart Assoc. 2020 Sep;9(17):e017171. doi: 10.1161/JAHA.120.017171. Epub 2020 Aug 27.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Rocuronium	Other / unclassified	1 mg/kg	Intravenous

Neuromuscular Blockade for Post-Cardiac Arrest Care

Summary

Timeline

Publications

Drugs

Indications