drugset / Trial / NCT02266537
Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male Volunteers
RandomizedParallel-groupDouble-blindTreatment
Summary
The study was aimed to evaluate the pharmacological effect of different α-antagonists on phenylephrine induced pupil size in healthy male volunteers as pharmacological basis for Intraoperative floppy iris syndrome (IFIS)
Timeline
- Start
- 2005-11
- Primary completion
- 2006-02
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alfuzosin | Small molecule | — | — |
| Subject | Doxazosin | Small molecule | — | — |
| Subject | Tamsulosin | Other / unclassified | — | — |
Indications
No indication recorded.