drugset / Trial / NCT02267239
Methodology Antiseptic Application, Influence on Oral Biofilm.
RandomizedCrossoverDouble-blindBasic science
Summary
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device. The first one using the immersion in the antiseptic solution, as much of the authors did in the past. And the second way doing a active mouthwash, as the manufacturer recommends. The study will compare two different antiseptic solutions, the chlorhexidine (0.2% Oraldine Perio) and the essential oils (Listerine Mentol) with the two different application and compared the bacterial vitality, thickness and covering grade between solutions and with a basal sample.
Timeline
- Start
- 2014-10
- Primary completion
- 2014-11
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 0.2 % | Oral |
| Comparator | Chlorhexidine | Small molecule | 1 ml | Oral |
| Comparator | Chlorhexidine | Small molecule | 10 ml | Oral |
| Comparator | Essential oils | Unknown | 1 ml | Oral |
| Comparator | Essential oils | Unknown | 20 ml | Oral |