drugset / Trial / NCT02267239

Methodology Antiseptic Application, Influence on Oral Biofilm.

NCT02267239

Phase 4 Unknown 15 enrolled University of Santiago de Compostela
RandomizedCrossoverDouble-blindBasic science

Summary

The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device. The first one using the immersion in the antiseptic solution, as much of the authors did in the past. And the second way doing a active mouthwash, as the manufacturer recommends. The study will compare two different antiseptic solutions, the chlorhexidine (0.2% Oraldine Perio) and the essential oils (Listerine Mentol) with the two different application and compared the bacterial vitality, thickness and covering grade between solutions and with a basal sample.

Timeline

Start
2014-10
Primary completion
2014-11
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 0.2 % Oral
Comparator Chlorhexidine Small molecule 1 ml Oral
Comparator Chlorhexidine Small molecule 10 ml Oral
Comparator Essential oils Unknown 1 ml Oral
Comparator Essential oils Unknown 20 ml Oral