drugset / Trial / NCT02270255
Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization
Phase 2
Completed
44 enrolled
McGill University Health Centre/Research Institute of the McGill University Health Centre
RandomizedParallel-groupDouble-blindTreatment
Summary
Uterine fibroid embolization (UFE) is now an accepted treatment of uterine fibroids. However the procedure is often very painful and, in many centres, patients are admitted overnight with patient controlled analgesic (PCA) pumps for pain control and discharged the next day with heavy pain medications. The goal of this study is to evaluate the effectiveness of a superior hypogastric nerve block (SHGNB) in controlling the pain post-UFE.
Timeline
- Start
- 2015-04
- Primary completion
- 2017-11-01
- Completion
- 2017-11-01
Publications
- Background Rasuli P, Jolly EE, Hammond I, French GJ, Preston R, Goulet S, Hamilton L, Tabib M. Superior hypogastric nerve block for pain control in outpatient uterine artery embolization. J Vasc Interv Radiol. 2004 Dec;15(12):1423-9. doi: 10.1097/01.RVI.0000137406.09852.A4.
- Yoon J, Valenti D, Muchantef K, Cabrera T, Toonsi F, Torres C, Bessissow A, Bandegi P, Boucher LM. Superior Hypogastric Nerve Block as Post-Uterine Artery Embolization Analgesia: A Randomized and Double-Blind Clinical Trial. Radiology. 2018 Oct;289(1):248-254. doi: 10.1148/radiol.2018172714. Epub 2018 Jul 10.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ropivacaine | Other / unclassified | 0.75 % | — |
| Subject | Ropivacaine | Other / unclassified | 20 ml | — |
| Comparator | Lidocaine | Other / unclassified | 1 % | Subcutaneous |
| Comparator | Lidocaine | Other / unclassified | 5 ml | Subcutaneous |