drugset / Trial / NCT02271230
Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure
RandomizedFactorialQuadruple-blindPrevention
Summary
This study will examine whether an intervention with vitamin D or fish oil supplements can reduce the risk of heart failure among adult men and women during a follow up period of up to five years (starting from the time of randomization into the parent VITAL trial). The investigators hypotheses are that both vitamin D and fish oil supplements will each reduce the risk of heart failure.
Timeline
- Start
- 2014-08
- Primary completion
- 2019-12
- Completion
- 2019-12
Outcome
Missed primary endpoint
registry Hazard Ratio (HR) 0.93 (95% CI 0.78 to 1.11) NCT02271230 ↗
registry Hazard Ratio (HR) 0.96 (95% CI 0.80 to 1.14) NCT02271230 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fish oil | Other / unclassified | 1 g | — |
| Subject | Vitamin D | Other / unclassified | 2000 iu | — |