Drugs / Fish oil
last change Jan 2026 re-read 2 minutes ago

Fish oil

Other / unclassified

Developed for
atrial fibrillation · alcohol dependence · epilepsy · pancreatic neoplasm · polycystic ovary syndrome · acute lung injury · adult acute respiratory distress syndrome · anorexia nervosa
+28 more · anxiety · atherosclerotic cardiovascular disease · atrial flutter · breast cancer · cardiovascular disorder · cholestasis · chronic pain syndrome · disorder of defective peroxisome oxidative status · end stage renal failure · heart failure · hyperlipidemia · hypertriglyceridemia · lung cancer · muscular atrophy · nicotine dependence · obesity disorder · parenteral nutrition-associated cholestasis · respiratory system disorder · rheumatoid arthritis · type 2 diabetes mellitus · asthma · autoimmune disease · infectious disease · NAFLD1 · schizoaffective disorder · schizophrenia · sitosterolemia · stroke disorder
Investigated by
University of Alberta · Brigham and Women's Hospital · Melbourne Health · Heart and Stroke Foundation of Canada · National Heart, Lung, and Blood Institute (NHLBI) · The University of Texas Health Science Center at San Antonio
+59 more · Vanderbilt University Medical Center · ASPEN Rhoads Research Foundation · Acute Respiratory Distress Syndrome Foundation · Alberta Diabetes Institute · American Heart Association · American Society for Parenteral and Enteral Nutrition · American Thoracic Society · Andrea Bonny · Assistance Publique - Hôpitaux de Paris · Associacao Fundo de Incentivo a Psicofarmcologia · B. Braun Medical SA · CURE Foundation · Canadian Institutes of Health Research (CIHR) · Charite University, Berlin, Germany · Chestnut Hill Health System · Children's Heart Center · Eduardo Ferriolli · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Federal University of Rio de Janeiro · Federal University of São Paulo · Foothills Medical Centre · French National Institute of Health and Medical Research · Fresenius Kabi · Fudan University · GCP-Service International West GmbH · GlaxoSmithKline · Hamilton Health Sciences Corporation · Indiana University · Institutos Madrileño de Estudios Avanzados IMDEA · Johane Allard · Johannes Gutenberg University Mainz · National Center for Complementary and Integrative Health (NCCIH) · National Institute of Allergy and Infectious Diseases (NIAID) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · Oncoclínicas · Region Skane · Robert Bosch-Krankenhaus Stuttgart · St. Boniface Hospital · St. Paul's Hospital, Canada · Stollery Children's Hospital Foundation · São Paulo Research Foundation · University Hospital Augsburg · University Hospital Goettingen · University Hospital Muenster · University Hospital Schleswig-Holstein · University Hospital, Bonn · University Hospitals, Leicester · University Medical Center Hamburg-Eppendorf · University Medical Center Rostock · University of Pennsylvania · University of Washington · VA Connecticut Healthcare System · Vanderbilt University · Wei Zhou · Women and Children's Health Research Institute, Canada · Wuerzburg University Hospital · Yale University · Zone Laboratories, Inc. · eCardio Diagnostics

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) SMOFLIPID 20% 2016-07-13 fda.gov

Trials 33 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT02538484 Apr 2016 → Mar 2020 breast cancer The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 13 trials
Phase 1 NCT06424860 Nov 2025 → Dec 2026 expected atherosclerotic cardiovascular disease, polycystic ovary syndrome University of Alberta Recruiting No outcome recorded
Phase 1 NCT03010917 Mar 2017 → May 2021 alcohol dependence Yale University Completed No outcome recorded
Phase 1 NCT04116203 Jun 2016 → Nov 2020 polycystic ovary syndrome University of Alberta Completed No outcome recorded
Phase 29 trials
Phase 2 NCT06279793 Feb 2024 → Mar 2030 expected GCP-Service International West GmbH Recruiting No outcome recorded
Phase 2 NCT04417595 Nov 2020 → Nov 2024 nicotine dependence Vanderbilt University Medical Center Completed No outcome recorded
Phase 2 NCT03077724 Mar 2017 → Jan 2018 pregnancy disorder Vanderbilt University Medical Center Completed No outcome recorded
Phase 2 NCT02420496 Jun 2016 cholestasis, liver disorder The University of Texas Health Science Center at San Antonio Withdrawn No outcome recorded
Phase 2 NCT01933243 Aug 2013 → Dec 2016 anorexia nervosa, anxiety Andrea Bonny Completed No outcome recorded
Phase 2 NCT01019382 Oct 2009 → Jun 2014 pancreatic neoplasm University Hospitals, Leicester Completed No outcome recorded
Phase 2 NCT00871377 May 2008 → May 2011 epilepsy National Center for Complementary and Integrative Health (NCCIH) Completed No outcome recorded
Phase 2 NCT00351533 Jul 2006 → Jan 2009 acute lung injury, adult acute respiratory distress syndrome University of Washington Completed No outcome recorded
Phase 2 NCT00076518 ? → Sep 2005 HIV infectious disease, hypertriglyceridemia National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00336908 Nov 2005 → Nov 2007 University of Alberta Completed No outcome recorded
Phase 35 trials
Phase 3 NCT02271230 Aug 2014 → Dec 2019 heart failure Brigham and Women's Hospital Completed No outcome recorded
Phase 3 NCT01565278 Feb 2012 → Aug 2015 parenteral nutrition-associated cholestasis Johane Allard Terminated No outcome recorded
Phase 3 NCT00447291 Dec 2006 → Mar 2010 obesity disorder Children's Heart Center Terminated No outcome recorded
Phase 3 NCT01211769 Feb 2006 → Jun 2008 alcohol dependence Federal University of São Paulo Completed No outcome recorded
Phase 3 NCT00299533 Feb 2004 → Sep 2006 epilepsy Brigham and Women's Hospital Completed No outcome recorded
Phase 45 trials
Phase 4 NCT01819961 Apr → Oct 2013 gastric neoplasm, liver and intrahepatic bile duct neoplasm, pancreatic neoplasm Wei Zhou Unknown No outcome recorded
Phase 4 NCT00552084 Nov 2007 → Apr 2014 atrial fibrillation Vanderbilt University Completed No outcome recorded
Phase 4 NCT00232245 Dec 2003 → Jan 2013 atrial fibrillation Melbourne Health Completed No outcome recorded
Phase 4 NCT00232232 Sep 2003 → Jul 2013 atrial fibrillation, atrial flutter Melbourne Health Completed No outcome recorded
Phase 4 NCT00232219 Jan 2003 → Nov 2013 atrial fibrillation Melbourne Health Completed No outcome recorded
Phase not applicable9 trials
NCT04965129 Nov 2022 → May 2024 lung cancer Federal University of Rio de Janeiro Unknown No outcome recorded
NCT03697499 Sep → Dec 2018 cardiovascular disorder, disorder of defective peroxisome oxidative status, respiratory system disorder Fudan University Completed No outcome recorded
NCT03462771 May → Jul 2018 muscular atrophy Eduardo Ferriolli Unknown No outcome recorded
NCT03048981 Mar → May 2017 atherosclerosis, platelet aggregation, spontaneous Region Skane Completed No outcome recorded
NCT01351805 Jul 2010 → Nov 2018 chronic pain syndrome, osteoarthritis, rheumatoid arthritis Brigham and Women's Hospital Completed No outcome recorded
NCT00682318 May 2008 → Nov 2028 expected University of Pennsylvania Active not recruiting No outcome recorded
NCT00365742 Apr → Jun 2006 hyperlipidemia Chestnut Hill Health System Completed No outcome recorded
NCT00308295 Apr → May 2006 end stage renal failure Indiana University Completed No outcome recorded
NCT00371982 Dec 2002 → Apr 2005 type 2 diabetes mellitus Assistance Publique - Hôpitaux de Paris Terminated No outcome recorded
Also used as a comparator or background therapy in 13 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00676156 Comparator Dec 2005 → Feb 2008 multiple sclerosis Oregon Health and Science University Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01594983 Comparator Jun 2012 → Jul 2013 Novartis Pharmaceuticals Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT01534663 Comparator Nov 2011 → Jul 2013 heart failure Columbia University Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05613803 Comparator Oct 2023 → Jan 2026 asthma Norfolk and Norwich University Hospitals NHS Foundation Trust Completed No outcome recorded
Phase 3 NCT04386577 Comparator Aug 2016 → Apr 2021 Augusta University Unknown No outcome recorded
Phase 3 NCT00072982 Comparator Nov 2006 → May 2008 rheumatoid arthritis National Center for Complementary and Integrative Health (NCCIH) Unknown No outcome recorded
Phase 41 trial
Phase 4 NCT02140788 Comparator May 2011 → Feb 2013 schizoaffective disorder, schizophrenia Duke University Terminated No outcome recorded
Phase not applicable6 trials
NCT01704859 Comparator Jun 2018 → Mar 2022 Brigham and Women's Hospital Completed No outcome recorded
NCT01948648 Comparator Feb 2018 → Apr 2021 sitosterolemia University of Manitoba Unknown No outcome recorded
NCT04070833 Comparator Aug 2016 → Sep 2018 stroke disorder Brigham and Women's Hospital Completed No outcome recorded
NCT01285362 Comparator Mar 2013 → Sep 2014 NAFLD1 Columbia University Completed No outcome recorded
NCT00914576 Comparator Apr 2011 → Jul 2013 Medical University of Vienna Completed No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2014-10-27 Otsuka Pharmaceutical Development & Commercialization, Inc. New product for Japanese women Nature Made Fish Oil Pearl Small Pearl-shaped Capsules Concentrated With Essential Nutritional Balance of Fish Oil otsuka.co.jp
2014-04-08 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces First Approval and Launch of Generic Lovaza® Capsules in the United States tevapharm.com

Evidence & citations 18 cited values

Every value below carries the sentence it was read from. 48 sources stand behind the page.

FieldValueCited text
Known as Fish oil “and Fish oil 1 gram - rich in omega 3 PUFAs; associated to a pill with 50mg of talcum powder, identical to the pill of naltrexone.” NCT01211769
40

“containing: Lutein 12mg, Vitamin C 300mg, Zinc 10mg, Ginko Biloba 10mg, Flavonoids 25mg, Fish oil 300mg” NCT00914576

Fish oil 2700 mg by mouth daily for 30 days.” NCT02538484

Fish Oil and Metformin” NCT06424860

NCT00371982

NCT00552084

NCT03462771

NCT02140788

NCT04070833

NCT01933243

NCT04965129

NCT01534663

NCT00072982

NCT00871377

NCT01594983

NCT04116203

NCT02420496

NCT00365742

NCT00076518

NCT03048981

NCT00336908

NCT03077724

NCT04386577

NCT00232245

NCT03010917

NCT01948648

NCT00232219

NCT01285362

NCT00299533

NCT06279793

NCT00676156

NCT03697499

NCT01819961

NCT00682318

NCT00232232

NCT00308295

NCT02271230

NCT00351533

NCT01565278

NCT01351805

NCT05613803

Known as Fish Oil (Containing Omega-3 Acids) ClinicalTrials.gov intervention name — accepted as the source's own label NCT04417595
Known as Fish oil (EPA/DHA) Fish oil (EPA/DHA) alone” NCT02271230
Known as Lovaza “n-3 LCPUFA supplements (Lovaza - GlaxoSmithKline (GSK) Pharmaceuticals, provided free of charge) at a dose of 4gr/day.” NCT01285362
Known as LovazaTM (former name: Omacor) “LovazaTM (former name: Omacor®)” NCT00682318
Known as Maxepa “Fish oil (Maxepa)” NCT00371982
Known as n-3 fatty acids “Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study.” PMID 25201887 Sep 2014
Known as Omacor “vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram)” NCT01704859
2

“Drug: Omega-3 fatty acids (fish oil), Omacor, 1 capsule per day.” NCT04386577

“Drug: Omega-3 fatty acids (fish oil) Omacor, 1 capsule per day.” NCT04070833

Known as Omega-3 “Fish Oil; Fish Oil 1200 Mg; Omega-3NCT04116203
Known as Omega-3 fatty acids “Drug: Omega-3 fatty acids (fish oil), Omacor, 1 capsule per day.” NCT04386577
1

“Drug: Omega-3 fatty acids (fish oil) Omacor, 1 capsule per day.” NCT04070833

Known as omega-3 fatty acids (fish oil) ClinicalTrials.gov intervention name — accepted as the source's own label NCT01758081
1

NCT01704859

Known as Omega-3 Fish Oil “This essentially consists of a 4 hour long infusion of purified omega-3 fish oil immediately after their gemcitabine chemotherapy has finished.” NCT01019382
1

NCT00447291

Known as Omegaven “It has been used parenterally (Omegaven) in young children with short bowel syndrome and PNALD with encouraging results.” NCT01565278
Known as Super Omega-3 “Fish oil (Super Omega-3, 4 caps/d) vs. placebo” NCT00299533
Known as Ω-3 polyunsaturated fatty acids “recommended standard intake of 1260 mg Ω-3 polyunsaturated fatty acids (fish oil) daily - but not echinacea, ginkgo biloba, ginseng, St. John's wort, valeriana or garlic - may...” PMID 26887420 Feb 2016
Action Inhibit “The mechanism by which EPA and DHA exert their anti-arrhythmia effect is due to inactivation of high frequency sodium and L-type calcium channels in the heart.” NCT00871377
Modality Other / unclassified “omega-3 polyunsaturated fatty acid (PUFA) supplementation” NCT01933243
Route Other “Liquid fish oil 7.5cc enterally every 6 hours” NCT00351533