drugset / Trial / NCT06424860

Fish Oil, Metformin and Heart Health in PCOS

NCT06424860

RandomizedParallel-groupSingle-blindTreatment

Summary

Women with Polycystic Ovary Syndrome (PCOS) have high testosterone levels which is associated with altered insulin-glucose metabolism and an adverse blood lipid profile, predisposing them to the development of Type II Diabetes and Cardiovascular Disease (CVD). This study will investigate the use of dietary fish oil supplementation as a safe and effective intervention, and as an adjunct therapy to standard of care treatment with metformin to improve heart health, blood lipids and insulin-glucose metabolism in women with PCOS, and those with PCOS and Type 2 Diabetes.

Timeline

Start
2025-11-01
Primary completion
2026-12-30
Completion
2027-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Fish oil Other / unclassified 4000 mg
Comparator Metformin Small molecule 1500 mg