drugset / Trial / NCT02278458

Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer

NCT02278458

Phase 1 Unknown 24 enrolled Betta Pharmaceuticals Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

Research Hypothesis: icotinib administered in combination with gemcitabine has an acceptable safety profile in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.The primary objective is to determine the safety profile of icotinib in combination with gemcitabine in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.

Timeline

Start
2014-10
Primary completion
2016-01
Completion
2016-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Icotinib Small molecule 125 mg
Subject Icotinib Small molecule 250 mg
Subject Icotinib Small molecule 375 mg
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous