drugset / Trial / NCT02278601

Comparison of Regimens MPIB, CIPCEA, PCEA

NCT02278601

Phase 3 Active not recruiting 839 enrolled KK Women's and Children's Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload. Women who have increased pain tend to have lower successful patient bolus demands when patient controlled epidural analgesia (PCEA) is utilised and have dysfunctional labour requiring obstetric intervention such as Caesarean or instrumental delivery. Labour pain often escalates and worsens as labour progresses requiring an individualized, variable, flexible analgesic regimen. Bolus epidural administrations have been shown to improve uniform spread of local anaesthetics with better pain relief, compared to fixed background infusions.

Timeline

Start
2015-01-28
Primary completion
2019-05-06
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Background Fentanyl Other / unclassified 2 ug/ml Other
Background Fentanyl Other / unclassified 0.1 % Other
Background Ropivacaine Other / unclassified 2 ug/ml Other
Background Ropivacaine Other / unclassified 0.1 % Other

Indications

No indication recorded.