drugset / Trial / NCT02286726

CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid Leukemia

NCT02286726

RandomizedParallel-groupOpen-labelTreatment

Summary

This phase II trial studies the best dose and how well liposomal cytarabine-daunorubicin CPX-351 (CPX-351) works in treating patients with newly diagnosed acute myeloid leukemia and who are at risk for not responding well to treatment. Liposomal cytarabine-daunorubicin CPX-351 combines two chemotherapy drugs that are known to help each other work better, and may work to stop the growth of cancer cells by blocking the cells from dividing.

Timeline

Start
2015-05-04
Primary completion
2020-01-22
Completion
2020-01-22

Drugs

EvaluationDrugModalityDoseRoute
Subject CPX-351 Other / unclassified 50 unknown Intravenous
Subject CPX-351 Other / unclassified 75 unknown Intravenous
Subject CPX-351 Other / unclassified 100 unknown Intravenous