Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty

Summary

This prospective randomized controlled trial was conducted To compare the efficacy of TNA in terms of total blood loss and the allogenic transfusion rate among the three study groups; intravenous alone, combined intravenous and low dose topical TNA and combined intravenous and high dose topical TNA. To evaluate the safety of each regimen in view of deep vein thrombosis and venous thromboembolism.

Timeline

Start

2014-11

Primary completion

2015-04

Completion

2015-06

Drugs

Indications