TAP Block With Liposomal Bupivacaine Versus Bupivacaine in Robotic Hysterectomy

Phase 4 Completed 60 enrolled University of Minnesota

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of the study is to compare pain control after robotic hysterectomy surgery using either liposomal bupivacaine or Bupivacaine when injected during a transversus abdominis plane (TAP) block. Robotic hysterectomy is when a patient is electively having robotic assisted removal of one's uterus. Both medications liposomal bupivacaine and Bupivacaine are standard of care in these types of surgeries.

Timeline

Start: 2013-06
Primary completion: 2014-10
Completion: 2014-10

Publications

Hutchins J, Delaney D, Vogel RI, Ghebre RG, Downs LS Jr, Carson L, Mullany S, Teoh D, Geller MA. Ultrasound guided subcostal transversus abdominis plane (TAP) infiltration with liposomal bupivacaine for patients undergoing robotic assisted hysterectomy: A prospective randomized controlled study. Gynecol Oncol. 2015 Sep;138(3):609-13. doi: 10.1016/j.ygyno.2015.06.008. Epub 2015 Jun 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	0.25 %	—
Subject	Bupivacaine	Other / unclassified	30 ml	—

Indications

No indication recorded.