drugset / Trial / NCT02295280

A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.

NCT02295280

Completed 70 enrolled St. Louis University
RandomizedParallel-groupOpen-labelPrevention

Summary

To determine if the intravenous administration of Metoclopramide and diphenhydramine in combination can effectively treat headaches in pregnant patients in those refractory to acetaminophen when compared to codeine

Timeline

Start
2012-01
Primary completion
2014-11
Completion
2014-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Codeine Small molecule 30 mg
Comparator Diphenhydramine Unknown 25 mg Intravenous
Comparator Metoclopramide Small molecule 10 mg Intravenous

Indications