Dexmedetomidine Effect on Mitochondrial Function

Summary

The investigators hypothesize that in addition to a known sympatholytic effect, intraoperative dexmedetomidine reduces adverse changes in mitochondrial function and structure attenuating ischaemia-reperfusion and end-organ injury for children with non cyanotic congenital heart defects having corrective heart surgery.

Timeline

Start

2014-11

Primary completion

2019-12

Completion

2019-12

Drugs

Indications