drugset / Trial / NCT02306954
Study of High Dose Interleukin-2 (IL-2) and Stereotactic Body Radiation (SBRT) in Patients With Metastatic Renal Cancer
Phase 2
Active not recruiting
84 enrolled
Providence Health & Services
Cytokine Working Group · collabPrometheus Laboratories · collab
RandomizedCrossoverOpen-labelTreatment
Summary
All patients will receive IL-2 (14 planned doses with an additional cycle 14 days after the first). Responding patients with regressing disease are eligible for up to 6 IL-2 cycles. Patients assigned to SBRT arm will receive two doses of SBRT on the Wednesday and Friday before the Monday on which IL-2 starts.
Timeline
- Start
- 2014-12
- Primary completion
- 2020-09-15
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | aldesleukin | Protein / enzyme biologic | 600000 iu/kg | Intravenous |