A Food Effect Phase I Study of the Sulfatinib in Healthy Subjects (HMPL-012)

NCT02320409 ↗

Phase 1 Completed 24 enrolled Hutchison Medipharma Limited

RandomizedCrossoverOpen-labelBasic science

Summary

The purpose of this study is to evaluate to determine the effect of food on the PK of a single dose of 250 mg Sulfatinib and its metabolites in healthy subjects.

Timeline

Start: 2014-12
Primary completion: 2015-01
Completion: 2015-04

Publications

Qian H, Wu X, Chen Q, Li T, Wang W, Jia J, Yu C, Li K, Sai Y, Su W, Liu Y. Effects of Food on the Pharmacokinetic Properties of Surufatinib: A Phase I, Single-dose, Randomized, Open-label Crossover Study in Healthy Subjects. Clin Ther. 2020 Sep;42(9):1778-1786. doi: 10.1016/j.clinthera.2020.07.010. Epub 2020 Aug 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Surufatinib	Small molecule	250 mg	Oral

Indications

No indication recorded.