drugset / Trial / NCT02322879
Protective Effects of Propylene Glycol in Daily Acetaminophen Dosing
RandomizedCrossoverDouble-blindPrevention
Summary
A purpose of this protocol is to is to compare the metabolites of the toxic bioactivating pathway after acetaminophen alone or acetaminophen followed by Propylene Glycol (PG) and to determine if it prevents the formation of the toxic metabolites of acetaminophen.
Timeline
- Start
- 2013-05
- Primary completion
- 2016-08
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propylene Glycol | Small molecule | 70 mg/kg | — |
| Background | First Treatment Period | Unknown | 4 g | — |