drugset / Trial / NCT02337192

Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients.

NCT02337192

Phase 1 Completed 24 enrolled University of Sao Paulo
RandomizedParallel-groupOpen-labelTreatment

Summary

We demonstrated the use of the Antimicrobial Photodynamic Therapy as a coadjutant oral decontamination agent. It was also shown that SDS surfactant improves the antibacterial action of APDT when using Curcumin as the photosensitizer. The decontamination levels obtained with APDT are comparable with the levels observed with the use of Chlorhexidine. The clinical relevancy is the control of oral microbial load which will improve the patients' quality of life and will decrease the possibility of cross contamination in the dental office.

Timeline

Start
2014-01
Primary completion
2014-06
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine gluconate Other / unclassified Other
Subject Curcumin Small molecule Other

Indications

No indication recorded.