drugset / Trial / NCT02337192
Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients.
RandomizedParallel-groupOpen-labelTreatment
Summary
We demonstrated the use of the Antimicrobial Photodynamic Therapy as a coadjutant oral decontamination agent. It was also shown that SDS surfactant improves the antibacterial action of APDT when using Curcumin as the photosensitizer. The decontamination levels obtained with APDT are comparable with the levels observed with the use of Chlorhexidine. The clinical relevancy is the control of oral microbial load which will improve the patients' quality of life and will decrease the possibility of cross contamination in the dental office.
Timeline
- Start
- 2014-01
- Primary completion
- 2014-06
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine gluconate | Other / unclassified | — | Other |
| Subject | Curcumin | Small molecule | — | Other |
Indications
No indication recorded.