drugset / Trial / NCT02343445

Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)

NCT02343445

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of the study is to evaluate the safety and tolerability of P-1037 and to determine whether the combination of P-1037 with hypertonic saline or P-1037 alone has a greater effect on lung function in patients with CF than placebo (0.17% saline).

Timeline

Start
2015-04
Primary completion
2016-02
Completion
2016-02

Drugs

EvaluationDrugModalityDoseRoute
Subject IDREVLORIDE Small molecule 85 ug Inhaled
Background Hypertonic saline Unknown 4.2 %

Indications