drugset / Trial / NCT02343445
Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of the study is to evaluate the safety and tolerability of P-1037 and to determine whether the combination of P-1037 with hypertonic saline or P-1037 alone has a greater effect on lung function in patients with CF than placebo (0.17% saline).
Timeline
- Start
- 2015-04
- Primary completion
- 2016-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | IDREVLORIDE | Small molecule | 85 ug | Inhaled |
| Background | Hypertonic saline | Unknown | 4.2 % | — |