A Randomized Controlled Trial Evaluating Sildenafil Citrate in Relieving Ureteral Stent Related Symptoms

Phase 4 Completed 94 enrolled Mansoura University

RandomizedParallel-groupDouble-blindTreatment

Summary

Despite its beneficial effect, ureteral stents may produce symptoms (such as hematuria, dysuria, frequency, urgency, urge incontinence and suprapubic or flank pain) that affect the quality of life in 70-80%. This study will be conducted to evaluate the role of Phosphodiestrase 5 inhibitor (Sildenafil Citrate) in relieving these symptoms.

Timeline

Start: 2014-03
Primary completion: 2016-11
Completion: 2016-11

Publications

Tharwat M, Elsaadany MM, Lashin AM, El-Nahas AR. A randomized controlled trial evaluating sildenafil citrate in relieving ureteral stent-related symptoms. World J Urol. 2018 Nov;36(11):1877-1881. doi: 10.1007/s00345-018-2339-y. Epub 2018 May 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Sildenafil	Unknown	50 mg	—

Indications

No indication recorded.