Safety, Tolerability and Host Response to Lactobacillus Johnsonii

Phase 1/2 Completed 42 enrolled University of Florida Juvenile Diabetes Research Foundation · collab

RandomizedParallel-groupDouble-blindBasic science

Summary

The purpose of this research study is to determine the effects of the probiotic, Lactobacillus johnsonii N6.2, on safety, gastrointestinal function, wellness, fecal bacteria and blood biomarkers in healthy individuals.

Timeline

Start: 2015-08
Primary completion: 2016-12
Completion: 2016-12

Publications

Marcial GE, Ford AL, Haller MJ, Gezan SA, Harrison NA, Cai D, Meyer JL, Perry DJ, Atkinson MA, Wasserfall CH, Garrett T, Gonzalez CF, Brusko TM, Dahl WJ, Lorca GL. Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults. Front Immunol. 2017 Jun 12;8:655. doi: 10.3389/fimmu.2017.00655. eCollection 2017.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Lactobacillus	Unknown	1e+10 unknown	Oral

Indications

No indication recorded.