Exparel Transversus Abdominis Plane Block vs Intrathecal Analgesia In Colorectal Surgery

Completed 209 enrolled Mayo Clinic

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is prospective, randomized trial in which EXPAREL TAP block is compared to standard IT opioid administration, in relieving postoperative pain, decreasing length of stay, and use of narcotic medication.

Timeline

Start: 2015-03
Primary completion: 2017-10
Completion: 2017-10

Publications

Colibaseanu DT, Osagiede O, Merchea A, Ball CT, Bojaxhi E, Panchamia JK, Jacob AK, Kelley SR, Naessens JM, Larson DW. Randomized clinical trial of liposomal bupivacaine transverse abdominis plane block versus intrathecal analgesia in colorectal surgery. Br J Surg. 2019 May;106(6):692-699. doi: 10.1002/bjs.11141. Epub 2019 Mar 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	133 mg	Other
Comparator	Hydromorphone	Other / unclassified	—	Intrathecal

Indications

No indication recorded.