drugset / Trial / NCT02359331
The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection
RandomizedCrossoverOpen-labelTreatment
Summary
As increasing the antibiotics resistance, the effectiveness of traditional Helicobacter pylori (H. pylori) therapies has been declined coincidentally. In this study, the investigators evaluated the efficacy of H. pylori eradication between a 7 days personalized therapy for H. pylori infection based on the results of antibiotics resistance by using H. pylori culture and minimal inhibitory concentration (MIC) and the 14 days bismuth contained quadruple 2nd rescue regimens, and the investigators analyzed the prevalence of the antibiotic resistance after 1st eradication of H. pylori in the tailored therapy group.
Timeline
- Start
- 2014-08
- Primary completion
- 2022-12-01
- Completion
- 2022-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | 1000 mg | — |
| Comparator | Metronidazole | Small molecule | 500 mg | — |
| Subject | Moxifloxacin | Small molecule | 400 mg | — |
| Comparator | Tetracycline | Unknown | 500 mg | — |
| Comparator | tripotassium dicitrate bismuthate | Unknown | 300 mg | — |