Tetracycline
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | ACHROMYCIN V | — | 1963-10-18 | fda.gov ↗ |
| Approved | US (FDA) | ACHROMYCIN | — | 1953-11-19 | fda.gov ↗ |
Trials 76 · started per year
Also used as a comparator or background therapy in 53 trials
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 129 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tetracycline | “14-day bismuth quadruple therapy (pantoprazole, bismuth subcitrate, tetracycline, and metronidazole for 14 days) or 14-day hybrid therapy (a 7-day dual therapy with...” PMID 28807915 ↗ Oct 2017126“Bacterial or Viral infection treatment may include: Doxycycline, Minocycline, Nitazoxanide, Hydroxychloroquine, Rifampin, Dapsone, Azithromycin, Tetracycline, Benzathine...” NCT05894954 ↗ “A is amoxicillin (1000 mg thrice daily), B is colloidal bismuth subcitrate (120 mg thrice daily), M is metronidazole (500 mg thrice daily), P is a proton pump inhibitor, i.e.,...” NCT06687473 ↗ “Fourteen-day esomeprazole, tripotassium dicitrate bismuthate, metronidazole and tetracycline (EBMT) therapy or esomeprazole, moxifloxacin and amoxicillin (MEA) therapy was...” PMID 26452405 ↗ Oct 2015 “Placement of CTZ antibiotic paste (chloramphenicol, tetracycline, zinc oxide mixed with eugenol) in the pulp chamber after irrigation with 3% sodium hypochlorite, followed by...” NCT07475364 ↗ “amoxicillin 1000mg bid for 10d, clarithromycin 500mg bid for 10d, metronidazole 500mg tid for 10d, tinidazole 500mg tid for 10d, levofloxacin 500mg qd for 10d, furazolidone...” NCT03571230 ↗ “Omeprazole 20 mg twice daily, in combination with bismuth subcitrate potassium (40 mg), metronidazole 125 mg and tetracycline 125 mg HCl. All patients must take 6 capsules of...” NCT00712413 ↗ “CTZ paste is composed of 62.5 mg of chloramphenicol, 62.5 mg of tetracycline and 125 mg of zinc oxide and manipulated with 0.1ml of eugenol in a sterile glass plate with...” NCT03650036 ↗ “Dose of two sensitive antibiotics are listed as follows : amoxicillin 1000mg bid, clarithromycin 500mg bid, tinidazole 500mg tid, levofloxacin 500mg qd, furazolidone 100mg bid,...” NCT03565484 ↗ “Multi-drug resistant strains: Esomeprazole 20 mg, Bismuth Potassium Citrate 220 mg, Amoxicillin 1 g, and either Furazolidone 0.1 g (twice daily) or Tetracycline 500 mg (four...” NCT06760065 ↗ “oral administration of tegoprazan-based bismuth quadruple therapy(tegoprazan 50 mg b.i.d, bismuth 300 mg q.i.d, metronidazole 500 mg t.i.d, tetracycline 500 mg q.i.d) for 14 days” NCT04674774 ↗ “Two antibiotics based on antibiotic sensitivity of H.pylori culture, including amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline and furazolidone.” NCT02894268 ↗ “Bismuth 300 mg (4 times a day), lansoprazole 30 mg (twice a day), metronidazole 500 mg (3 times a day), and tetracycline 500 mg (4 times a day) for 10 days” NCT02112214 ↗ “rabeprazole 20mg b.i.d + amoxicillin 1000mg b.i.d x 5 days + rabeprazole 20mg b.i.d + clarithromycin 500mg b.i.d + tetracycline 1000mg b.i.d x last 5 days.” NCT01573975 ↗ “Patients resistant to both clarithromycin and levofloxacin are assigned to the Tetracycline Group (receiving vonoprazan, amoxicillin, and tetracycline)” NCT07533422 ↗ “a capsule containing 3 agents (Pylera®) containing 125mg metronidazole, 140mg bismuth subcitrate potassium, and 125mg tetracycline was made available.” NCT02045251 ↗ “Lansoprazole 30mg, 2 times a day + Bismuth 300mg, 4 times a day + Tetracycline 500mg, 4 times a day + Metronidazole 500mg, 3 times a day for 10 days” NCT02557932 ↗ “bismuth quadruple therapy: include rabeprazole 20 mg bid, bismuth 120 mg qid, metronidazole 500 mg tid, and tetracycline 500 mg qid, for 14 days” NCT05332444 ↗ “bismuth subcitrate 120 mg four times daily, and tetracycline 500 mg four times daily, and metronidazole 250 mg four times daily for 14 days” NCT02547038 ↗ “priority antibiotic selection was as follow: Amoxicillin \> Clarithromycin \> Levofloxacin \>Tetracycline \> Furazolidone \> Metronidazole.” NCT02689583 ↗ “esomeprazole 40 mg and bismuth 300mg twice daily, tetracycline 500 mg four times daily, metronidazole 500mg three times daily for 10 days” NCT04006340 ↗ “rabeprazole 20 mg b.i.d. plus tripotassium dicitrate bismuthate 300 mg, tetracycline 500 mg and metronidazole 250 mg q.i.d. for 10 days” NCT03779074 ↗ “Antibiotics are selected from Amoxicillin, Tetracycline, Furazolidone, Levofloxacin, Clarithromycin, Tinidazole, Metronidazole.” NCT05133193 ↗ “D1-D10: (esomeprazole 40mg bid + Dibismuth trioxide 120mg qid + metronidazole 500mg tid + tetracycline 500mg qid) for 10 days” NCT03148366 ↗ “D1-D10: (esomeprazole 40mg bid + dibismuth trioxide 120mg qid + metronidazole 500mg tid + tetracycline 500mg qid) for 10 days” NCT03156855 ↗ “Esomeprazole 40mg bid + bismuth subsalicylate 420mg 6/6h + metronidazole 375mg 6/6h + tetracycline 375mg 6/6h, for 10 days” NCT05449028 ↗ “Patients will a 10-day course of bismuth, metronidazole, tetracycline four times daily, and vonoprazan 20 mg twice daily.” NCT07165444 ↗ “Bismuth Quadruple therapy consists of Bismuth subcitrate 120mg QDS, Tetracycline 500mg QDS and Metronidazole 500mg TDS.” NCT07010744 ↗ “esomeprazole 40 mg bid., tripotassium dicitrate bismuthate 300mg qid, tetracycline 500 mg qid, levofloxacin 500 mg qd.” NCT03779087 ↗ “Tetracycline 500mg four times Omeprazole 30mg twice Bismuth 600mg twice Metronidazole 500mg three times for 10 days” NCT01938534 ↗ “lansoprazole 30mg bid + colloidal bismuth subcitrate 300mg tid + metronidazole 500mg tid + tetracycline 500mg tid” NCT01906879 ↗ “powder included dexamethasone, diphenhydramine, tetracycline, metronidazole, nystatin, zinc oxide, and karaya gum” NCT02142543 ↗ “esomeprazole 20mg b.d., bismuth subcitrate 120mg q.i.d., tetracycline 250mg q.i.d. and metronidazole 250mg q.i.d.” NCT01306786 ↗ “Omeprazole 40 mg BID, Metronidazole 400 mg TID, Tetracycline 500 mg QID, Bismuth subsalicylate for 14 days.” NCT07312721 ↗ “Bismuth 524mg QID, Metronidazole 500mg QID, Tetracycline 500MG QID, and Omeprazole 20 mg QID for 14 days.” NCT07104318 ↗ “esomeprazole 40 mg b.d., bismuth 120 mg q.d.s., tetracycline 500 mg q.d.s., and levofloxacin 500 mg o.d.” NCT02978157 ↗ “Tid group: Amoxicillin 1000mg bid+ Tetracycline 500mg tid+ Bismuth + Esomeprazole 40mg bid” NCT05432115 ↗ “Patients received topical Phenytoin 5%+ Tetracycline after necrotic bone debridement .” NCT03269214 ↗ “Scheme 5 Amoxicillin 1000 mg, 2 times/d; Tetracycline 500mg, 3 times/d or 4 times/d” NCT04660123 ↗ “Tetracycline (Huanan Brand, Guangdong Huanan Pharmaceutical Co. LTD.) 500mg qid” NCT05586113 ↗ “tetracycline 500 mg q.d.s. and levofloxacin 500 mg o.d.) for 14 days” NCT02547025 ↗ “and tetracycline (500 mg) four times daily” NCT01967329 ↗ “Tetracycline® 500 mg qid 7 days (D1-D7)” NCT02373280 ↗ “T is tetracycline (500 mg thrice daily)” NCT06687499 ↗ “Tetracycline® 500 mg qid 7 days (D1-D7)” NCT02373280 ↗ “tetracycline 500mg three times a day” NCT04713670 ↗ “4. Tetracycline: 500mg, 3 times/day” NCT06943794 ↗ “Tetracycline, 500mg, PO, QID, 1wk” NCT02759029 ↗ “3. Tetracycline, 500 mg, bid” NCT01032655 ↗ “Tetracycline 500mg qid po” NCT04723472 ↗ “tetracycline 500 mg QID” NCT01643785 ↗ “tetracycline 500mg qid” NCT01760824 ↗ “Tetracycline 500mg tid” NCT07068607 ↗ “tetracycline 500 mg” NCT02547012 ↗ “Drug: Tetracycline” NCT07139366 ↗ “T etracycline” NCT02099240 ↗ |
| Known as | Huanan Brand | “Tetracycline (Huanan Brand, Guangdong Huanan Pharmaceutical Co. LTD.) 500mg qid” NCT05586113 ↗ |
| Known as | tetracycline hydrochloride | “each containing 420 mg of bismuth subcitrate potassium, 375 mg of metronidazole and 375 mg of tetracycline hydrochloride” NCT03146325 ↗ |
| Known as | TTC | “treatment with tetracycline (TTC) solution” NCT02057926 ↗ |
| Route | Oral | “oral tetracycline qid on days 4-10” NCT00003151 ↗ |