drugset / Trial / NCT03658746

Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection

NCT03658746

Phase 4 Completed 420 enrolled Shandong University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess efficacy of 14-day antimicrobial susceptibility test guided quadruple therapy for the rescue treatment of Helicobacter pylori infection, then comparing it with 14-day empirical therapy according to personal medication history.

Timeline

Start
2019-01-01
Primary completion
2019-12-31
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Clarithromycin Small molecule 500 mg
Comparator Furazolidone Small molecule 100 mg
Comparator Levofloxacin Small molecule 500 mg
Subject Metronidazole Small molecule 500 mg
Subject Tetracycline Unknown 500 mg
Subject tinidazole Small molecule 500 mg
Background Amoxicillin Other / unclassified 1000 mg
Background Rabeprazole Small molecule 10 mg
Background colloidal bismuth pectin Unknown 200 mg