drugset / Trial / NCT03658746

Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection

NCT03658746 ↗

Phase 4 Completed 420 enrolled Shandong University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess efficacy of 14-day antimicrobial susceptibility test guided quadruple therapy for the rescue treatment of Helicobacter pylori infection, then comparing it with 14-day empirical therapy according to personal medication history.

Timeline

Start
2019-01-01
Primary completion
2019-12-31
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Clarithromycin Small molecule 500 mg —
Comparator Furazolidone Small molecule 100 mg —
Comparator Levofloxacin Small molecule 500 mg —
Subject Metronidazole Small molecule 500 mg —
Subject Tetracycline Unknown 500 mg —
Subject tinidazole Small molecule 500 mg —
Background Amoxicillin Other / unclassified 1000 mg —
Background Rabeprazole Small molecule 10 mg —
Background colloidal bismuth pectin Unknown 200 mg —