drugset / Trial / NCT07165444
Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to compare the eradication rate, safety, and patient adherence between potassium-competitive acid blockers (P-CABs) and proton pump inhibitor-based bismuth quadruple therapy in patients with Helicobacter pylori infection.
Timeline
- Start
- 2025-09-11
- Primary completion
- 2026-02-01
- Completion
- 2026-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Rabeprazole | Small molecule | 20 mg | — |
| Subject | Vonoprazan | Other / unclassified | 20 mg | — |
| Comparator | Bismuth Potassium Citrate | Unknown | — | — |
| Comparator | Metronidazole | Small molecule | — | — |
| Comparator | Tetracycline | Unknown | — | — |