drugset / Trial / NCT05850117
Efficacies of Tetracycline-levofloxacin, Standard Bismuth, Amoxicillin-levofloxacin Quadruple Therapy for H.p
RandomizedParallel-groupOpen-labelTreatment
Summary
1. Compare the efficacy of "Tetracycline combined with levofloxacin quadruple therapy", "standard tincture quadruple therapy" and "amoxicillin combined with levofloxacin quadruple therapy" on the second line of Helicobacter pylori sterilization. 2. To investigate the drug resistance of Helicobacter pylori and the host genotypes of CYP2C19 and IL-1B-511 on the sterilizing effect of three second-line Helicobacter pylori.
Timeline
- Start
- 2020-02-10
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 500 mg | — |
| Comparator | Levofloxacin | Small molecule | 500 mg | — |
| Comparator | Metronidazole | Small molecule | 250 mg | — |
| Comparator | Tetracycline | Unknown | 500 mg | — |
| Comparator | Esomeprazole | Small molecule | 40 mg | — |
| Comparator | tripotassium dicitrate bismuthate | Unknown | 300 mg | — |
Indications
No indication recorded.