drugset / Trial / NCT02360059

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

NCT02360059 ↗

Phase 2 Terminated 1 enrolled M.D. Anderson Cancer Center
RandomizedParallel-groupDouble-blindTreatment

Summary

The goal of this clinical research study is to learn if metformin can help to control nerve damage (loss of motor or sensory function) that may be caused by treatment with paclitaxel in patients with breast cancer. In this study, metformin will be compared to a placebo. A placebo is not a drug. It looks like the study drug, but it is not designed to treat any disease or illness. It is designed to be compared with a study drug to learn if the study drug has any real effect.

Timeline

Start
2015-10
Primary completion
2016-09
Completion
2016-09

Outcome

Outcome not reported

Stopped (Enrollment): “Low Accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 1000 mg Oral

Indications