drugset / Trial / NCT02363621

Evaluation of Inflammation and Pain Post Injection of Ranibizumab vs Aflibercept in Patients With DME

NCT02363621

Phase 2 Completed 101 enrolled Arshad Khanani Genentech, Inc. · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

This study is designed to compare the post injection inflammation and pain seen after intravitreal injections of ranibizumab 0.3mg and aflibercept 2.0mg in patients with DME. The investigators will be evaluating patients (1-7 days) post injections for: 1\. Intraocular inflammation (defined as anterior chamber and/or vitreous cells 2. Pain (as measured on a standardized pain scale).

Timeline

Start
2015-01
Primary completion
2017-10
Completion
2017-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aflibercept Protein / enzyme biologic 2 mg Intravitreal
Comparator Ranibizumab Monoclonal antibody 0.3 mg Intravitreal