drugset / Trial / NCT02383563
Metformin for HIV Inflammation
Phase 2
Unknown
12 enrolled
University of Hawaii
National Institute of General Medical Sciences (NIGMS) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This proposal seeks to assess the impact of 24 weeks of metformin on non-calcified plaques and calcified plaques assessed by coronary CT angiography, and on whether these changes can be explained by metformin-induced phenotypic and secretory changes of monocytes.
Timeline
- Start
- 2015-02
- Primary completion
- 2016-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 1000 mg | — |