drugset / Trial / NCT02396225

Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration

NCT02396225

RandomizedParallel-groupOpen-labelOther

Summary

Concentrations of voriconazole in pulmonary epithelial lining fluid and in serum are compared after inhalation of 40 mg voriconazole b.i.d. for two days or oral intake of voriconazole tablets 400 mg bid for 1 day followed by 200 mg b.i.d. for one day, respectively.

Timeline

Start
2015-03
Primary completion
2016-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Voriconazole Small molecule 40 mg Inhaled
Subject Voriconazole Small molecule 200 mg Inhaled