drugset / Trial / NCT02396225
Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration
RandomizedParallel-groupOpen-labelOther
Summary
Concentrations of voriconazole in pulmonary epithelial lining fluid and in serum are compared after inhalation of 40 mg voriconazole b.i.d. for two days or oral intake of voriconazole tablets 400 mg bid for 1 day followed by 200 mg b.i.d. for one day, respectively.
Timeline
- Start
- 2015-03
- Primary completion
- 2016-12
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Voriconazole | Small molecule | 40 mg | Inhaled |
| Subject | Voriconazole | Small molecule | 200 mg | Inhaled |