drugset / Trial / NCT02396979
Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia
Phase 4
Completed
300 enrolled
Yale University
National Institute on Drug Abuse (NIDA) · collabUniversity of Malaya · collab
RandomizedFactorialOpen-labelTreatment
Summary
The purpose of this study is to evaluate the relative impact a medical drug (methadone) or behavioral counseling program (Holistic Health Recovery Program) or both (methadone and Holistic Health Recovery Program) has on reducing HIV-related risk behaviors and illicit drug use among opioid-dependent, HIV-infected individuals in prison when given 90 to 180 days prior to leaving prison.
Timeline
- Start
- 2010-01
- Primary completion
- 2014-12
- Completion
- 2014-12
Publications
- Mobley AM, Wegman MP, Bazazi AR, Shenoi SV, Bromberg DJ, Ahmad A, Kamarulzaman A, Altice FL. Prescribing methadone in prison predicts linkage to HIV care after release from prison: A randomized and patient preference trial. Int J Drug Policy. 2025 Mar;137:104733. doi: 10.1016/j.drugpo.2025.104733. Epub 2025 Feb 8.
- Bazazi AR, Culbert GJ, Wegman MP, Heimer R, Kamarulzaman A, Altice FL. Impact of prerelease methadone on mortality among people with HIV and opioid use disorder after prison release: results from a randomized and participant choice open-label trial in Malaysia. BMC Infect Dis. 2022 Nov 11;22(1):837. doi: 10.1186/s12879-022-07804-6.
- Chandra DK, Bazazi AR, Nahaboo Solim MA, Kamarulzaman A, Altice FL, Culbert GJ. Retention in clinical trials after prison release: results from a clinical trial with incarcerated men with HIV and opioid dependence in Malaysia. HIV Res Clin Pract. 2019 Feb;20(1):12-23. doi: 10.1080/15284336.2019.1603433. Epub 2019 May 1.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methadone | Other / unclassified | — | — |