drugset / Trial / NCT02404064

Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?

NCT02404064

Unknown 288 enrolled HaEmek Medical Center, Israel
RandomizedParallel-groupOpen-labelPrevention

Summary

To compare surgical site infection (SSI) rate in patients undergoing laparoscopic appendectomy for acute uncomplicated appendicitis and treated with single dose regime of antibiotics versus group of patients undergoing laparoscopic appendectomy without antibiotics treatment. Patient will be given either single dose of perioperative antibiotics or no antibiotics before surgery.

Timeline

Start
2015-03
Primary completion
2015-03
Completion
2017-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefazolin Small molecule 1 g Intravenous
Subject Metronidazole Small molecule 500 mg Intravenous

Indications