Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)

Summary

The purpose of this study is to see if salsalate, an Nuclear factor-kappaB (NF-κB) mediated inflammation inhibitor, or carvedilol, an α- and β-blocker, will protect against free fatty acid induced hypertension, insulin resistance, endothelial dysfunction, inflammation and oxidative stress, and autonomic dysfunction in obese normotensive subjects.

Timeline

Start

2009-07

Primary completion

2011-03

Completion

2011-03

Drugs

Indications