Intralipid

also known as INTRALIPID (soy bean oil) · Intralipid 20% · Intralipid 20% (20% i.v. fat emulsion) · Intralipid 20% (a 20% intravenous fat emulsion) · Intravenous Lipid Emulsion

Other / unclassified

Developed for: hypertriglyceridemia · infertility disorder · pulmonary immaturity · antiphospholipid syndrome · cholestasis · habitual spontaneous abortion · hepatic coma · low implantation of placenta
+12 more
· organophosphate poisoning · parenteral nutrition-associated cholestasis · poisoning · pregnancy loss, recurrent, 4 · acute respiratory distress syndrome · bilirubin encephalopathy · chronic intestinal failure · esophageal atresia · liver disorder · metabolic disease · protein-energy malnutrition · short bowel syndrome
Investigated by: American Diabetes Association · Beth Israel Deaconess Medical Center · Emory University · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · University Health Network, Toronto · Woman's Health University Hospital, Egypt
+33 more
· Ahmed Mohamed Bahaa Eldin Ahmed · Ain Shams Maternity Hospital · Ain Shams University · Amani Hassan Abdel-Wahab · Assistance Publique - Hôpitaux de Paris · Cairo University · French National Institute of Health and Medical Research · Fresenius Kabi · Hospital for Special Surgery, New York · Indiana University · King Fahad Medical City · OSF Healthcare System · Oregon Health and Science University · Pennington Biomedical Research Center · Primary Children's Hospital · Radboud University Medical Center · Seattle Children's Hospital · Shanghai Jiao Tong University School of Medicine · Tanta University · The University of Texas Health Science Center at San Antonio · The University of Texas Health Science Center, Houston · University of Alberta · University of Colorado, Denver · University of Copenhagen · University of Florida · University of Kansas Medical Center · University of Michigan · University of Minnesota · University of North Carolina, Chapel Hill · University of Pennsylvania · Wei Cai · Yale University · ZonMw: The Netherlands Organisation for Health Research and Development

Trials 34

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030203120322033

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT04832009	May 2022 → Aug 2026 overdue	hypertensive disorder	University of Kansas Medical Center	Recruiting	No outcome recorded
Phase 0	NCT03479671	Jan 2020 → Nov 2024	type 2 diabetes mellitus	University of Pennsylvania	Completed	No outcome recorded
Phase 0	NCT02697201	Jul 2016 → May 2021	—	Pennington Biomedical Research Center	Completed	No outcome recorded
Phase 12 trials
Phase 1	NCT05553405	Jan 2024 → Jan 2033	obesity disorder	Yale University	Withdrawn	No outcome recorded
Phase 1	NCT03132779	May 2017 → Jan 2018	pregnancy loss, recurrent, 4	Ahmed Mohamed Bahaa Eldin Ahmed	Unknown	No outcome recorded
Phase 1/21 trial
Phase 1/2	NCT04328337	Dec 2020 → Jun 2026 overdue	obesity disorder	University of North Carolina, Chapel Hill	Recruiting	No outcome recorded
Phase 22 trials · 1 missed
Phase 2	NCT03374163	Jan 2015 → Jun 2017	infertility disorder	King Fahad Medical City	Completed	No outcome recorded
Phase 2	NCT01602250	Jan 2011 → Aug 2013	poisoning	Assistance Publique - Hôpitaux de Paris	Completed	Missed primary
Phase 2/33 trials
Phase 2/3	NCT04393103	Apr 2024 → Jan 2025	organophosphate poisoning	Amani Hassan Abdel-Wahab	Withdrawn	No outcome recorded
Phase 2/3	NCT01540591	Feb 2012 → Sep 2013	infertility disorder	Cairo University	Completed	No outcome recorded
Phase 2/3	NCT00989339	Nov 2009 → Dec 2011	diabetes mellitus, hypertensive disorder, obesity disorder	Emory University	Withdrawn	No outcome recorded
Phase 33 trials · 1 missed
Phase 3	NCT03387579	Nov 2018 → Mar 2021	parenteral nutrition-associated cholestasis	Indiana University	Completed	Missed primary
Phase 3	NCT02357576	May 2016 → Oct 2017	cholestasis	University of Michigan	Completed	No outcome recorded
Phase 3	NCT00451646	Oct 2007 → Oct 2008	—	Fresenius Kabi	Completed	No outcome recorded
Phase 48 trials
Phase 4	NCT04274803	Apr 2020 → May 2021	antiphospholipid syndrome	Tanta University	Withdrawn	No outcome recorded Stop: Enrollment
Phase 4	NCT03968822	Jul 2019 → Oct 2026 expected	—	Hospital for Special Surgery, New York	Active not recruiting	No outcome recorded
Phase 4	NCT03857646	Mar 2019 → Jun 2020	—	The University of Texas Health Science Center, Houston	Completed	No outcome recorded
Phase 4	NCT01788540	Feb 2013 → Aug 2016	habitual spontaneous abortion	Woman's Health University Hospital, Egypt	Completed	No outcome recorded
Phase 4	NCT01786759	Oct 2012 → May 2013	pulmonary immaturity	Shanghai Jiao Tong University School of Medicine	Unknown	No outcome recorded
Phase 4	NCT01683162	Jul → Dec 2012	pulmonary immaturity	Wei Cai	Unknown	No outcome recorded
Phase 4	NCT01679561	Feb → Aug 2012	low implantation of placenta	Woman's Health University Hospital, Egypt	Withdrawn	No outcome recorded
Phase 4	NCT00188773	Jan 2004 → Aug 2007	metabolic syndrome X	University Health Network, Toronto	Completed	No outcome recorded
Phase not applicable12 trials · 3 missed
—	NCT04807634	Mar → Sep 2021	hepatic coma	Ain Shams University	Unknown	No outcome recorded
—	NCT04558190	Sep 2020 → Nov 2021	—	University of Copenhagen	Completed	No outcome recorded
—	NCT02517307	Feb 2016 → Jan 2021	carnitine palmitoyl transferase II deficiency, myopathic form, long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, medium chain acyl-CoA dehydrogenase deficiency, mitochondrial trifunctional protein deficiency +1	Oregon Health and Science University	Completed	Missed primary
—	NCT02463812	May 2015 → Apr 2017	—	University of Alberta	Withdrawn	No outcome recorded Stop: Enrollment
—	NCT01520454	Nov 2011 → Dec 2013	obesity disorder	Beth Israel Deaconess Medical Center	Completed	No outcome recorded
—	NCT02406586	Jul 2009 → Mar 2011	diabetes mellitus, hypertensive disorder	Emory University	Completed	No outcome recorded
—	NCT00786487	Jan 2009 → Jan 2014	—	University of Minnesota	Completed	Missed primary
—	NCT01096446	Apr 2008 → May 2010	hyperglycemia, hypertriglyceridemia	OSF Healthcare System	Terminated	Missed primary
—	NCT01740817	Jan 2008 → Dec 2013	diabetes mellitus, obesity disorder	The University of Texas Health Science Center at San Antonio	Completed	No outcome recorded
—	NCT00278928	Jan 2006 → Apr 2007	hypertriglyceridemia	Beth Israel Deaconess Medical Center	Terminated	No outcome recorded
—	NCT00184899	Aug 2005 → Aug 2006	metabolic syndrome X, obesity disorder	Radboud University Medical Center	Completed	No outcome recorded
—	NCT00152945	Apr 2005 → Jul 2008	—	University Health Network, Toronto	Completed	No outcome recorded

Comparator or background therapy33 trials
Phase 1	NCT02240498 Background	Sep 2014 → Sep 2023	abscess	University of Rochester	Completed	No outcome recorded
Phase 1	NCT00512629 Comparator	Jul 2007 → Dec 2011	parenteral nutrition-associated cholestasis	Boston Children's Hospital	Completed	No outcome recorded
Phase 1/2	NCT02865785 Comparator	Jul 2016 → Jul 2017	infertility disorder	Ain Shams University	Unknown	No outcome recorded
Phase 1/2	NCT02365285 Background	Mar 2015 → Oct 2017	obesity disorder	Vanderbilt University Medical Center	Completed	Met primary
Phase 2	NCT07179003 Background	Apr 2026 → Mar 2031 expected	breast abscess	University of Rochester	Not yet recruiting	No outcome recorded
Phase 2	NCT04584983 Comparator	Feb 2021 → Mar 2024 overdue	bilirubin encephalopathy	The University of Texas Health Science Center, Houston	Active not recruiting	No outcome recorded
Phase 2	NCT03127345 Comparator	Sep 2019 → Sep 2023	esophageal atresia	Boston Children's Hospital	Withdrawn	No outcome recorded Stop: Business
Phase 2	NCT01096771 Comparator	Jun 2010 → Nov 2012	acute respiratory distress syndrome	Methodist Research Institute, Indianapolis	Terminated	No outcome recorded Stop: Enrollment
Phase 2	NCT00793195 Comparator	Jan 2009 → Sep 2011	chronic intestinal failure, intestinal motility disease, short bowel syndrome	The Hospital for Sick Children	Unknown	Met primary
Phase 2/3	NCT02807727 Comparator	Jan 2017 → Jun 2018	—	Nkanyiso Hadebe	Unknown	No outcome recorded
Phase 2/3	NCT00672854 Comparator	Nov 2008 → Dec 2010	—	Emory University	Completed	No outcome recorded
Phase 2/3	NCT02185729 Comparator	Jun 2008 → Mar 2012	metabolic disease	Emory University	Completed	No outcome recorded
Phase 3	NCT04466618 Comparator	Apr 2021 → Dec 2022	type 2 diabetes mellitus	Adrian Vella	Completed	No outcome recorded
Phase 3	NCT02579265 Comparator	Dec 2015 → Apr 2020	—	Fresenius Kabi	Terminated	Missed primary
Phase 3	NCT02663453 Comparator	Dec 2013 → Dec 2015	cholestasis	Thammasat University	Completed	No outcome recorded
Phase 3	NCT01916798 Comparator	May 2013 → Jan 2015	infertility disorder	Cairo University	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT04555044 Comparator	Jan 2021 → Oct 2022	metabolic disease	Baxter Healthcare Corporation	Completed	No outcome recorded
Phase 4	NCT04806425 Comparator	Oct 2020 → Feb 2021	—	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT03563222 Comparator	Dec 2019 → Nov 2020	protein-energy malnutrition	Fresenius Kabi	Terminated	No outcome recorded
Phase 4	NCT03054948 Comparator	Feb 2017 → Mar 2018	short bowel syndrome	Mayo Clinic	Withdrawn	No outcome recorded
Phase 4	NCT02476994 Comparator	May 2015 → Oct 2016	metabolic disease	Baxter Healthcare Corporation	Terminated	No outcome recorded
Phase 4	NCT02349594 Comparator	Jan 2014 → May 2015	Crohn disease	Radboud University Medical Center	Completed	No outcome recorded
Phase 4	NCT01943409 Comparator	Jul 2013 → Dec 2019	cancer, ileus, protein-energy malnutrition	Johane Allard	Completed	No outcome recorded
Phase 4	NCT02487940 Comparator	Oct 2012 → Apr 2015	infertility disorder	Dar El Teb Institute	Completed	No outcome recorded
Phase 4	NCT01585935 Comparator	Jun 2012 → Jun 2015	cholestasis, neurodevelopmental disorder	Medical University of Vienna	Completed	Missed primary
Phase 4	NCT01373918 Comparator	Dec 2010 → Jul 2014	cholestasis	University of California, Los Angeles	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT01054989 Comparator	Mar 2009 → Sep 2011	—	German Diabetes Center	Completed	No outcome recorded
Phase 4	NCT01115179 Comparator	Mar → Dec 2005	—	University Hospital, Geneva	Completed	No outcome recorded
Phase 4	NCT00738023 Comparator	Mar 2004 → Dec 2009	hypertensive disorder, type 2 diabetes mellitus	Emory University	Completed	No outcome recorded
—	NCT02653092 Comparator	Jun 2016 → Dec 2023 overdue	hyperinsulinism, hypogonadotropic hypogonadism, infertility disorder, obesity disorder	University of Colorado, Denver	Active not recruiting	No outcome recorded
—	NCT01284049 Comparator	Nov 2011 → Apr 2015	liver disorder	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
—	NCT00589888 Comparator	Aug 2006 → Apr 2008	hypertensive disorder	Emory University	Completed	No outcome recorded
—	NCT00753142 Comparator	Mar 2004 → Dec 2009	type 2 diabetes mellitus	Emory University	Completed	No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 67 sources stand behind the page.

Field	Value	Cited text
Known as	INTRALIPID	“We conducted an interventional trial using either a 6-h lipid (20% Intralipid at 90 ml/h) or glycerol (2.25 g/100 ml at 90 ml/h) infusion along with a concurrent...” PMID 22639293 ↗ May 2012 67 “Sixty (30/30) premature neonates (age 3-7 days, gestational age ≤ 34 weeks, birth weights 1000-2500 g) received parenteral nutrition (PN) with either SMOFlipid 20% (study...” PMID 20531018 ↗ Oct 2010 “The purpose of the study is to test whether INTRALIPID administered at reperfusion can limit myocardial reperfusion injury as measured by cTnI release in patients undergoing...” NCT02807727 ↗ “The cavity will then be filled with sterile 1% Intralipid solution to gently distend the cavity and, through efficient light scattering, to homogenize the light dose to the...” NCT02240498 ↗ “The next morning, after an overnight fast, they will receive, in random order, Intralipid 20%, ClinOleic 20% or normal saline at 20 ml/hr for 24 hr.” NCT00989339 ↗ “For the experimental group, Intralipid will be increased by 0.5 grams/kg/day until a goal rate of 3 grams/kg/day is achieved.” NCT01096446 ↗ “This lipid emulsion will be either Intralipid or Nutrilipid.” NCT07179003 ↗ “In most cases standard therapy will be IntraLipid.” NCT03054948 ↗ “Fat infusion (Intralipid) over 6 hours” NCT01054989 ↗ NCT00278928 ↗ NCT02487940 ↗ Show 57 more sources
Known as	INTRALIPID (soy bean oil)	“INTRALIPID (soy bean oil)” NCT01585935 ↗
Known as	Intralipid 20%	“Administration of Intralipid 20%® at a dose ranging between 0.5 and 1 g/kg/infusion during 12 weeks.” NCT01284049 ↗
Known as	Intralipid 20% (20% i.v. fat emulsion)	“Intralipid® 20% (20% i.v. fat emulsion)” NCT03563222 ↗
Known as	Intralipid 20% (a 20% intravenous fat emulsion)	“Intralipid® 20% (a 20% intravenous fat emulsion)” NCT02579265 ↗
Known as	Intravenous Lipid Emulsion	“Intravenous Lipid Emulsion (Intralipid 20%)” NCT04807634 ↗
Modality	Other / unclassified	“intralipid (a synthetic triglyceride emulsion that provides a source of fatty acids)” NCT00152945 ↗
Route	Intravenous	“intravenous infusion” NCT00152945 ↗