drugset
drugset / Trial / NCT03968822

Intralipid® 20% for Reversal of Local Anesthetics

NCT03968822 ↗

Phase 4 Active not recruiting 18 enrolled Hospital for Special Surgery, New York
RandomizedCrossoverDouble-blindOther

Summary

In order to determine if Intralipid 20% can be used to reverse the effects of local anesthetics, the investigators will recruit 18 volunteers who will be asked to come to HSS for two study visits. Small amounts of local anesthetics will be injected into the volunteers' thighs during both visits. During one visit volunteers will receive Intralipid 20% and during the other visit they will receive a saline solution. The study team will measure how quickly normal sensation returns to the thighs when the volunteers get Intralipid 20% compared to saline.

Timeline

Start
2019-07-26
Primary completion
2026-10
Completion
2026-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Intralipid Other / unclassified 20 % Intravenous
Subject Intralipid Other / unclassified 250 ml Intravenous
Background Bupivacaine Other / unclassified 0.25 % Other
Background Bupivacaine Other / unclassified 0.5 % Other
Background Bupivacaine Other / unclassified 3 ml Other
Background Lidocaine Other / unclassified 1 % Other
Background Lidocaine Other / unclassified 2 % Other
Background Lidocaine Other / unclassified 3 ml Other

Indications

No indication recorded.