drugset / Trial / NCT03479671
Low Dose Fat-Induced Insulin Resistance
Non-randomizedSequentialOpen-labelBasic science
Summary
The primary goal of this study is to determine the dose of fatty acids that acutely induces mild insulin resistance in healthy volunteers. We hypothesize that a low-dose of fatty acid infusion (Intralipid/heparin) will cause a mild insulin resistance. The dose of fatty acid infusion that reliably causes mild insulin resistance will be selected for use in future studies.
Timeline
- Start
- 2020-01-01
- Primary completion
- 2024-11-19
- Completion
- 2024-11-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Intralipid | Other / unclassified | 30 ml | Intravenous |
| Subject | Intralipid | Other / unclassified | 60 ml | Intravenous |