drugset / Trial / NCT02408445

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

NCT02408445

Phase 4 Completed 20 enrolled University of Colorado, Denver
RandomizedParallel-groupSingle-blindTreatment

Summary

This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about body composition (muscle and fat) and male hormones and look at the effect of testosterone shots on body composition. The Investigators know that older boys and men with Klinefelter syndrome often have more fat compared to muscle than adults without Klinefelter syndrome, but we do not know if this difference is present at birth or develops over time. The Investigators will learn if body composition and motor skills are improved with testosterone treatment in infants with Klinefelter syndrome.

Timeline

Start
2015-05-08
Primary completion
2018-01-31
Completion
2020-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Testosterone Cypionate Small molecule 200 mg/ml Intramuscular

Indications