drugset / Trial / NCT02415699

DC-CIK Immunotherapy Plus Chemotherapy vs Chemotherapy Alone in the Adjuvant Treatment of Stage III Colorectal Cancer

NCT02415699

Phase 2/3 Unknown 100 enrolled Sixth Affiliated Hospital, Sun Yat-sen University
RandomizedSingle-groupOpen-labelTreatment

Summary

Stage III colorectal cancer constitutes more than half of the colorectal patients, and the prognosis does not improve much recently although varies of adjuvant drugs have been tried. DC-CIK immunotherapy has been proved to improve survival in cancer patients, but its role in stage III colorectal cancer patients stains unclear. The investigators study will focus on the efficacy and safety of DC-CIK immunotherapy plus chemotherapy in the adjuvant treatment of stage III colorectal cancer, compared with chemotherapy alone.

Timeline

Start
2015-08
Primary completion
2017-07
Completion
2020-07

Drugs

EvaluationDrugModalityDoseRoute
Subject DC-CIK Cell therapy
Background Leucovorin Small molecule
Background Oxaliplatin Small molecule
Background fluorouracil Small molecule

Indications