drugset / Trial / NCT02420210

Bendamustine, Obinutuzumab, and Dexamethasone in Older Patients With Diffuse Large B-cell Lymphoma

NCT02420210 ↗

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well bendamustine hydrochloride, obinutuzumab, and dexamethasone work in treating older patients with diffuse large B-cell lymphoma. Drugs used in chemotherapy, such as bendamustine hydrochloride and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as obinutuzumab, may find cancer cells and help kill them. Giving bendamustine hydrochloride, obinutuzumab, and dexamethasone may kill more cancer cells.

Timeline

Start
2015-11
Primary completion
2016-08
Completion
2016-08

Outcome

Outcome not reported

Stopped (Business): “Trials was stopped early due to lack of funding.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule — Intravenous
Subject Dexamethasone Small molecule — Oral
Subject Obinutuzumab Monoclonal antibody — Intravenous