drugset / Trial / NCT02429440

Adjuvant Antigen Specific Immunotherapy in Patients With Advanced Renal Cell Carcinoma Using Tumor Associated Peptides

NCT02429440

Phase 1/2 Unknown 40 enrolled University Hospital Tuebingen
RandomizedParallel-groupOpen-labelTreatment

Summary

Clinical Phase I/II study to investigate the feasibility and tolerability of synthetic adjuvant peptide immunisation in combination with immune adjuvants (granulocyte macrophage colony stimulating factor; Montanide ISA-51) in patients with advanced renal cell cancer (RCC).

Timeline

Start
2005-05
Primary completion
2017-10
Completion
2018-06

Drugs

EvaluationDrugModalityDoseRoute
Subject NY-ESO-1 Protein / enzyme biologic Subcutaneous
Comparator incomplete Freund's adjuvant Other / unclassified Subcutaneous
Subject sargramostim Protein / enzyme biologic Intramuscular

Indications