drugset / Trial / NCT02434146

Topical Phenylephrine Solution in Preventing Oral Mucosa in Bone Marrow Transplant Patients Receiving Cyclophosphamide and Total Body Radiation Therapy

NCT02434146

Phase 1/2 Terminated 3 enrolled University of Wisconsin, Madison
NaSingle-groupOpen-labelSupportive care

Summary

This phase I/II trial studies the safety of topical phenylephrine solution and to see how well it works in preventing oral mucosa (mouth sores) in bone marrow transplant patients receiving cyclophosphamide and total body radiation therapy. Topical phenylephrine solution may prevent or lessen the severity of oral mucosa in patients receiving cyclophosphamide and total body radiation prior to undergoing a bone marrow transplant.

Timeline

Start
2015-05-14
Primary completion
2016-04-27
Completion
2017-01-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Phenylephrine Small molecule Topical