drugset / Trial / NCT02436473
Clinical Efficacy of Fluoride Toothpastes Using an In Situ Caries Model
Withdrawn
GlaxoSmithKline
RandomizedCrossoverSingle-blindTreatment
Summary
The purpose of this study is to evaluate the effect of the test toothpaste containing 1150 parts per million (ppm) of fluoride (F) on the mineral content of demineralized enamel specimens, in an in situ caries model system, by comparing the differences in net remineralization change (ΔM) following use of the test toothpaste with a fluoride free (0 ppm F) reference control toothpaste.
Timeline
- Start
- 2015-12
- Primary completion
- 2016-11
- Completion
- 2016-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluoride | Other / unclassified | 250 ppm | Topical |
| Comparator | Fluoride | Other / unclassified | 1150 ppm | Topical |