drugset / Trial / NCT02436473

Clinical Efficacy of Fluoride Toothpastes Using an In Situ Caries Model

NCT02436473

Withdrawn GlaxoSmithKline
RandomizedCrossoverSingle-blindTreatment

Summary

The purpose of this study is to evaluate the effect of the test toothpaste containing 1150 parts per million (ppm) of fluoride (F) on the mineral content of demineralized enamel specimens, in an in situ caries model system, by comparing the differences in net remineralization change (ΔM) following use of the test toothpaste with a fluoride free (0 ppm F) reference control toothpaste.

Timeline

Start
2015-12
Primary completion
2016-11
Completion
2016-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fluoride Other / unclassified 250 ppm Topical
Comparator Fluoride Other / unclassified 1150 ppm Topical

Indications