drugset / Trial / NCT02436694

Nerve Blocks With Dexamethasone and Local Anaesthetic to Improve Postoperative Analgesia

NCT02436694 ↗

Unknown 56 enrolled Centro Hospitalar do Porto
RandomizedParallel-groupSingle-blindTreatment

Summary

Can the association of dexamethasone to the local anaesthetic in a single-shot femoral and sciatic nerve block improve analgesia postoperatively in patients submitted to total knee arthroplasty? Primary aim: Evaluate the efficacy of the association of dexamethasone to the local anaesthetic in a SSFNB and SSSNB in reducing pain scores, assessed by VAS. Outcome measures: Mean pain scores in both groups. Secondary aims: Evaluate opioid consumption in the postoperative period (8- 12h, 24h, 48h) and assess incidence of side effects and complications (numbness, paraesthesias, weakness, site infection, haematoma and falls).

Timeline

Start
2015-04
Primary completion
2016-04
Completion
2016-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 4 mg Other
Background Ropivacaine Other / unclassified 0.2 % Other
Background Ropivacaine Other / unclassified 0.375 % Other
Background Ropivacaine Other / unclassified 20 ml Other
Background Ropivacaine Other / unclassified 30 ml Other