drugset / Trial / NCT02436694
Nerve Blocks With Dexamethasone and Local Anaesthetic to Improve Postoperative Analgesia
RandomizedParallel-groupSingle-blindTreatment
Summary
Can the association of dexamethasone to the local anaesthetic in a single-shot femoral and sciatic nerve block improve analgesia postoperatively in patients submitted to total knee arthroplasty? Primary aim: Evaluate the efficacy of the association of dexamethasone to the local anaesthetic in a SSFNB and SSSNB in reducing pain scores, assessed by VAS. Outcome measures: Mean pain scores in both groups. Secondary aims: Evaluate opioid consumption in the postoperative period (8- 12h, 24h, 48h) and assess incidence of side effects and complications (numbness, paraesthesias, weakness, site infection, haematoma and falls).
Timeline
- Start
- 2015-04
- Primary completion
- 2016-04
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 4 mg | Other |
| Background | Ropivacaine | Other / unclassified | 0.2 % | Other |
| Background | Ropivacaine | Other / unclassified | 0.375 % | Other |
| Background | Ropivacaine | Other / unclassified | 20 ml | Other |
| Background | Ropivacaine | Other / unclassified | 30 ml | Other |