drugset / Trial / NCT02438566

Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery

NCT02438566

Phase 3 Unknown 118 enrolled The New England Baptist Hospital
RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this research is to determine if the oral form of a medication (tranexamic acid) to reduce bleeding can be used in place of an intravenous (IV) form, to learn the best way to give tranexamic acid: either a pill by mouth, or a solution by vein.

Timeline

Start
2015-04
Primary completion
2016-04
Completion
2017-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tranexamic Acid Small molecule 1 g Oral
Comparator Tranexamic Acid Small molecule 1950 mg Oral

Indications